Structure of PDB 8oyc Chain B

Receptor sequence

>8oycB (length=425) Species: 192952 (Methanosarcina mazei Go1) [Search protein sequence]

MNPKRIRALKSPVVYWMSRDQRAEDNWALLFSRAIAKEANVPVVVVFCLT
DEFLEAGIRQYEFMLKGLQELEVSLSRKKIPSFFLRGDPGEKISRFVKDY
NAGTLVTDFSPLRIKNQWIEKVISISIPFFEVDAHNVVPCWEASQKHEYA
AHTFRPKLYALLPEFLEEFPELEPNSVTPENKDPLFEPWHFEPGEKAAKK
VMESFIADRLDSYGALRNDPTKNMLSNLSPYLHFGQISSQRVVLEVEKAE
SNPGSKKAFLDEILIWKEISDNFCYYNPGYDGFESFPSWAKESLNAHRND
VRSHIYTLEEFEAGKTHDPLWNASQMELLSTGKMHGYMRMYWAKKILEWS
ESPEKALEIAICLNDRYELDGRDPNGYAGIAWSIGGVHDRAWGEREVTGK
IRYMSYEGCKRKFDVKLYIEKYSAL

3D structure

PDB

8oyc Time-resolved crystallography captures light-driven DNA repair

Chain

Resolution

2.5 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

4.1.99.3: deoxyribodipyrimidine photo-lyase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	B	A160 H161 R164 R256 E301 W305 W421 R429 R441 Y442 M443 S444 R450 K451	A151 H152 R155 R217 E262 W266 W382 R390 R402 Y403 M404 S405 R411 K412
BS02	dna	B	K155 Y158 W328 R429 W431 K439 R450	K146 Y149 W289 R390 W392 K400 R411
BS03	FDA	B	Y252 L264 S265 N266 S268 F298 E301 W305 K306 K372 R378 M379 N403 D409 N414 G415	Y213 L225 S226 N227 S229 F259 E262 W266 K267 K333 R339 M340 N364 D370 N375 G376

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0003904	deoxyribodipyrimidine photo-lyase activity
GO:0016829	lyase activity

	Biological Process
GO:0000719	photoreactive repair
GO:0006281	DNA repair

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:8oyc, PDBe:8oyc, PDBj:8oyc
PDBsum	8oyc
PubMed	38033070
UniProt	Q8PYK9

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