Structure of PDB 8oy9 Chain B

Receptor sequence

>8oy9B (length=421) Species: 192952 (Methanosarcina mazei Go1) [Search protein sequence]

MNPKRIRALKSQGDGPVVYWMSRDQRAEDNWALLFSRAIAKEANVPVVVV
FCLTDEFLEAGIRQYEFMLKGLQELEVSLSRKKIPSFFLRGDPGEKISRF
VKDYNAGTLVTDFSPLRIKNQWIEKVISGISIPFFEVDAHNVVPCWEASQ
KHEYAAHTFRPKLYALLPEFLEEFPELEPNSVTPFEPWHFEPGEKAAKKV
MESFIADRLDSYGALRNDPTKNMLSNLSPYLHFGQISSQRVVLEVEKAES
NPGSKKAFLDEILIWKEISDNFCYYNPGYDGFESFPSWAKESLNAHRNDV
RSHIYTLEEFEAGKTHDPLWNASQMELLSTGKMHGYMRMYWAKKILEWSE
SPEKALEIAICLNDRYELDGRDPNGYAGIAWSIGGVHDRAWGEREVTGKI
RYMSYEGCKRKFDVKLYIEKY

3D structure

PDB

8oy9 Time-resolved crystallography captures light-driven DNA repair

Chain

Resolution

2.24 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

4.1.99.3: deoxyribodipyrimidine photo-lyase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	B	A160 H161 R164 R256 N257 E301 W305 M379 R429 R441 Y442 M443 S444 G447 R450 K451	A156 H157 R160 R216 N217 E261 W265 M339 R389 R401 Y402 M403 S404 G407 R410 K411
BS02	dna	B	T162 R429 A430 W431 E433 K439 R450	T158 R389 A390 W391 E393 K399 R410
BS03	FDA	B	Y252 S265 N266 S268 L271 F298 E301 W305 K306 K372 R378 N403 D409 N414 G415 I419	Y212 S225 N226 S228 L231 F258 E261 W265 K266 K332 R338 N363 D369 N374 G375 I379

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0003904	deoxyribodipyrimidine photo-lyase activity
GO:0016829	lyase activity

	Biological Process
GO:0000719	photoreactive repair
GO:0006281	DNA repair

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:8oy9, PDBe:8oy9, PDBj:8oy9
PDBsum	8oy9
PubMed	38033070
UniProt	Q8PYK9

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