Structure of PDB 8oy7 Chain B

Receptor sequence

>8oy7B (length=428) Species: 192952 (Methanosarcina mazei Go1) [Search protein sequence]

MNPKRIRALKSGKQGDGPVVYWMSRDQRAEDNWALLFSRAIAKEANVPVV
VVFCLTDEFLEAGIRQYEFMLKGLQELEVSLSRKKIPSFFLRGDPGEKIS
RFVKDYNAGTLVTDFSPLRIKNQWIEKVISGISIPFFEVDAHNVVPCWEA
SQKHEYAAHTFRPKLYALLPEFLEEFPELEPNSVTPDPLFEPWHFEPGEK
AAKKVMESFIADRLDSYGALRNDPTKNMLSNLSPYLHFGQISSQRVVLEV
EKAESNPGSKKAFLDEILIWKEISDNFCYYNPGYDGFESFPSWAKESLNA
HRNDVRSHIYTLEEFEAGKTHDPLWNASQMELLSTGKMHGYMRMYWAKKI
LEWSESPEKALEIAICLNDRYELDGRDPNGYAGIAWSIGGVHDRAWGERE
VTGKIRYMSYEGCKRKFDVKLYIEKYSA

3D structure

PDB

8oy7 Time-resolved crystallography captures light-driven DNA repair

Chain

Resolution

2.36 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

4.1.99.3: deoxyribodipyrimidine photo-lyase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	B	A160 H161 N257 E301 W305 Y376 M379 W421 R429 W431 R441 Y442 M443 S444 G447 R450 K451	A158 H159 N222 E266 W270 Y341 M344 W386 R394 W396 R406 Y407 M408 S409 G412 R415 K416
BS02	dna	B	Y158 T162 W431 K439	Y156 T160 W396 K404
BS03	FDA	B	Y252 L264 S265 N266 S268 F298 E301 W305 K306 K372 R378 N403 D409 G410 N414 G415 G418	Y217 L229 S230 N231 S233 F263 E266 W270 K271 K337 R343 N368 D374 G375 N379 G380 G383

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0003904	deoxyribodipyrimidine photo-lyase activity
GO:0016829	lyase activity

	Biological Process
GO:0000719	photoreactive repair
GO:0006281	DNA repair

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:8oy7, PDBe:8oy7, PDBj:8oy7
PDBsum	8oy7
PubMed	38033070
UniProt	Q8PYK9

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