Structure of PDB 8owy Chain B

Receptor sequence
>8owyB (length=163) Species: 9606 (Homo sapiens) [Search protein sequence]
SMEAQKNWDLFYKRHWTTREDQKLTMLEAGCGVGNCLFPLLEEDPNIFAY
ACDFSPRAIEYVDTERCKVFQCDLTHVPPESVDVVMLIFVLSAVHPDKMH
LVLQNIYKVLKPGKSVLFRDYGLTRSYFFTDDFLAQLFMDTGYEEVVNEY
VFRRVFLQSKFLK
3D structure
PDB8owy Structural basis of the cooperation between the m3C RNA-methyltransferase METTL6 with SerRS amino-acyl-synthetase for tRNA recognition
ChainB
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH B W45 Y49 W62 E85 G87 C88 G89 D110 F111 D136 L137 I157 V159 A162 W8 Y12 W16 E28 G30 C31 G32 D53 F54 D73 L74 I88 V90 A93
External links
PDB RCSB:8owy, PDBe:8owy, PDBj:8owy
PDBsum8owy
PubMed38918637
UniProtQ8TCB7|METL6_HUMAN tRNA N(3)-methylcytidine methyltransferase METTL6 (Gene Name=METTL6)

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