Structure of PDB 8osc Chain B

Receptor sequence
>8oscB (length=126) Species: 9606 (Homo sapiens) [Search protein sequence]
GMRPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTGGDRLIHEQDLEW
LQQADVVVAEVTQPSLGVGYELGRAVAFNKRILCLFRPQSGRVLSAMIRG
AADGSRFQVWDYEEGEVEALLDRYFE
3D structure
PDB8osc Human 2'-Deoxynucleoside 5'-Phosphate N -Hydrolase 1: Mechanism of 2'-Deoxyuridine 5'-Monophosphate Hydrolysis.
ChainB
Resolution1.42 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.2.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UMP B C26 G27 S28 I29 R30 I76 D80 S98 G100 E104 C9 G10 S11 I12 R13 I43 D47 S65 G67 E71
Gene Ontology
Molecular Function
GO:0070694 deoxyribonucleoside 5'-monophosphate N-glycosidase activity
Biological Process
GO:0009159 deoxyribonucleoside monophosphate catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8osc, PDBe:8osc, PDBj:8osc
PDBsum8osc
PubMed37582341
UniProtO43598|DNPH1_HUMAN 5-hydroxymethyl-dUMP N-hydrolase (Gene Name=DNPH1)

[Back to BioLiP]