Structure of PDB 8oq2 Chain B

Receptor sequence

>8oq2B (length=381) Species: 921 (Ancylobacter novellus)

SAKILCVLYDDPVDGYPKTYARDDLPKIDHYPGGQTLPTPKAIDFTPGAL
LGSVSGELGLRKYLEANGHTFVVTSDKDGPDSVFERELVDADVVISQPFW
PAYLTPERIAKAKNLKLALTAGIGSDHVDLQSAIDRGITVAEVTYCNSIS
VAEHVVMMILGLVRNYIPSHDWARKGGWNIADCVEHSYDLEGMTVGSVGA
GRIGLAVLRRLAPFDVKLHYTQRHRLPEAVEKELGLVWHDTREDMYPHCD
VVTLNVPLHPETEHMINDETLKLFKRGAYIVNTARGKLADRDAIVRAIES
GQLAGYAGDVWFPQPAPKDHPWRTMKWEGMTPHISGTSLSAQARYAAGTR
EILECFFEGRPIRDEYLIVQGGALAGTGAKV

3D structure

• PDB: 8oq2 Binding of NADP to a formate dehydrogenase from Starkeya novella.
• Chain: B
• Resolution: 1.91 Å

Enzymatic activity

• Enzyme Commision number: 1.17.1.9: formate dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAP	B	I124 N148 V152 G202 R203 I204 Q223 R224 H225 V257 P258 T284 A285 R286 H334 S336 G337	I123 N147 V151 G201 R202 I203 Q222 R223 H224 V256 P257 T283 A284 R285 H333 S335 G336
BS02	AZI	B	P99 F100 I124 R286 H334	P98 F99 I123 R285 H333
BS03	AZI	B	D25 K28	D24 K27
BS04	AZI	B	Y32 Q36 P39 T145 Y367	Y31 Q35 P38 T144 Y366

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0008863 formate dehydrogenase (NAD+) activity
• GO:0016491 oxidoreductase activity
• GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
• GO:0051287 NAD binding

Biological Process

• GO:0042183 formate catabolic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:8oq2, PDBe:8oq2, PDBj:8oq2
• PDBsum: 8oq2
• UniProt: D7A8L2