Structure of PDB 8om4 Chain B

Receptor sequence

>8om4B (length=342) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

PNNNDEVMLLQQKLLYDEIRSELKSLSQVPEDEILPELKKSLEQDKLSDK
EQQLEAELSDFFRNYALLNKLFDSTKPYPNLIPSANDKPYSSQELFLRQL
NHSMRTAKLGATISKVYYPHKDIFYPPLPENITVESLMSAGVHLGQSTSL
WRSSTQSYIYGEYKGIHIIDLNQTLSYLKRAAKVVEGVSESGGIILFLGT
RQGQKRGLEEAAKKTHGYYVSTRWIPGTLTNSTEISGIWEKQEIDSNDNP
TERALSPNETSKQVKPDLLVVLNPTENRNALLEAIKSRVPTIAIIDTDSE
PSLVTYPIPGNDDSLRSVNFLLGVLARAGQRGLQNRLARNNE

3D structure

PDB

8om4 METTL17 is an Fe-S cluster checkpoint for mitochondrial translation.

Chain

Resolution

2.32 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	B	Q150 H153 H171 K172 F175 Y176 P177 S200 S204 R257 E261 K264 K265 R274 I276 P277 G278 T281 N282 E285 N330 E334 K337 R378 Q381	Q99 H102 H120 K121 F124 Y125 P126 S149 S153 R206 E210 K213 K214 R223 I225 P226 G227 T230 N231 E234 N279 E283 K286 R327 Q330
BS02	MG	B	Q197 D347 D363 D364	Q146 D296 D312 D313

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation
GO:0032543	mitochondrial translation

	Cellular Component
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005763	mitochondrial small ribosomal subunit
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:8om4, PDBe:8om4, PDBj:8om4
PDBsum	8om4
PubMed	38199006
UniProt	P32902\|RT04_YEAST Small ribosomal subunit protein uS2m (Gene Name=MRP4)

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