Structure of PDB 8odw Chain B

Receptor sequence

>8odwB (length=569) Species: 1445505 (Gynuella sunshinyii)

KRICIIGAGPAGLVMAKSLLEEGHEPVIYETESVLGGIWNYNSTRFQNSA
DTSFFSDFPADTTDGFFLGVDQVRAYLQAYASRFDIHQYIHYNSKIIAVT
EHGDQWKVDIGQQQTRYFDGVAMCHGRYKHPFIPTIPGLDQFQGEVLHSG
QYYDNRIFAGKRVLVIGNGVSGMDIAEEASHVASAVFWSMRLRLVLPRMV
GYLPNDFISPANLLISKDNSIIMERLKNSMPEYYECYQKSGLFPSLEDFR
ANPFVHINDGVIQRVAEGAIQTHVEDIERFTGRGCIFSASGTHIENIDMV
VLCTGYDNSQVKQFSMRDDFAMGLFYRQNPSLVNTYGLQNVGTTGTLPYL
EMVARWYAQIISGNYTLDAEELNHRAGEGEIVVAPLANVIMGLKLGLLPD
PKTEFQAFWRCLNYPSFPPMYRLRGPHADPQAQSVLSRSVQRSLIQQGEH
DSQLQTVKHRLLAGLGEEVMQALLARQEISQEEYLQAQRCGENAIVLSWD
TQVIRPVELMSQTLKLDVGQITADRHLSDYGFSSVTLTAFSRKITDEYNI
RLQPFVFLEYTTLKALTDF

3D structure

• PDB: 8odw Modular Oxime Formation by a trans-AT Polyketide Synthase.
• Chain: B
• Resolution: 3.07 Å

Enzymatic activity

• Enzyme Commision number: 2.3.1.39: [acyl-carrier-protein] S-malonyltransferase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	B	I18 P22 A23 Y41 E42 T43 G49 I50 W51 T65 F67 Q68 K116 I117 H149 G150 Y365 G374 T375	I6 P10 A11 Y29 E30 T31 G37 I38 W39 T44 F46 Q47 K95 I96 H125 G126 Y336 G345 T346
BS02	NAP	B	Q68 Y152 G191 N192 G193 V194 S195 R215 R218 C328 T329 V370 T375	Q47 Y128 G167 N168 G169 V170 S171 R191 R193 C303 T304 V341 T346

Gene Ontology

Molecular Function

• GO:0004499 N,N-dimethylaniline monooxygenase activity
• GO:0031177 phosphopantetheine binding
• GO:0050660 flavin adenine dinucleotide binding
• GO:0050661 NADP binding

External links

• PDB: RCSB:8odw, PDBe:8odw, PDBj:8odw
• PDBsum: 8odw
• PubMed: 37216334
• UniProt: A0A0C5VQJ2