Structure of PDB 8kib Chain B

Receptor sequence
>8kibB (length=411) Species: 10090 (Mus musculus) [Search protein sequence]
RKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDAT
NDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNI
LGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVPGPGKV
EITYTPKDGTQKVTYMVHDFEEGGGVAMGMYNQDKSIEDFAHSSFQMALS
KGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQKICYEHRLID
DMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKT
VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTEL
SFFAKALEDVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLG
ENLKAKLAQAK
3D structure
PDB8kib NADP+-dependent cytosolic isocitrate dehydrogenase complexed with oxaloacetate
ChainB
Resolution1.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP B D253 Q257 K260 D251 Q255 K258
BS02 OAA B H170 D171 H168 D169
BS03 NAP B T75 T77 N96 L288 H309 G310 T311 V312 T313 H315 T327 N328 T73 T75 N94 L286 H307 G308 T309 V310 T311 H313 T325 N326
BS04 OAA B T77 S94 N96 R100 R132 T75 S92 N94 R98 R130
External links
PDB RCSB:8kib, PDBe:8kib, PDBj:8kib
PDBsum8kib
PubMed
UniProtO88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytoplasmic (Gene Name=Idh1)

[Back to BioLiP]