Structure of PDB 8k79 Chain B

Receptor sequence
>8k79B (length=244) Species: 9031 (Gallus gallus) [Search protein sequence]
LEVKLGQGEVWMGTWNGTTRVAIKTLKPGTMSPFLQEAQVMKKLRHEKLV
QLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASG
MAYVERMNYVHRDLRAANILVGENLVCKVADFRLFPIKWTAPEAALYGRF
TIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPE
SLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
3D structure
PDB8k79 Structural insight into the macrocyclic inhibitor TPX-0022 of c-Met and c-Src.
ChainB
Resolution2.8 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 IYC B A293 T338 M341 G344 N391 L393 A403 D404 A22 T65 M68 G71 N118 L120 A130 D131
External links
PDB RCSB:8k79, PDBe:8k79, PDBj:8k79
PDBsum8k79
PubMed38074469
UniProtP00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

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