Structure of PDB 8k66 Chain B

Receptor sequence
>8k66B (length=443) Species: 39947 (Oryza sativa Japonica Group) [Search protein sequence]
YFVNFVVLAHRFIALHIHPFWIQLSYFLLISILGSVLLMFLKPSNPEFRP
GYIDMLFLSTSALTLSSLITIEMEVLSSSQIVVITLLMLLGGEVFVSFLG
LMLRLRSKRLRWFLGFVVFSYFVVIHVAGFLLVLWYISRVSSAKAPLKKK
GINIALFSFSVTVSSFANVGLVPTNENMAIFSKNPGLLLLFIGQILAGNT
LYPLFLRLLIWFLGKVTKLRELKLMIKNPEELQYDYLLPKLPTAFLASTV
IGLMASLVTLFGAVDWNSSVFDGLSSYQKIINALFMAVNARHSGENSIDC
SLIAPAVLVLFIILMYLPPSTTFALSKLGLVVQNLAFSQLACISVFVIVA
FITERSRLRNDPLNFSALNMIFEIISAYGNVGLSTGYSCSRLQKLHPGSI
CQDKPYSLSGWWSDEGKLLLVFVMLYGRLKAFTKGTGEYWRLW
3D structure
PDB8k66 Structural insights into ion selectivity and transport mechanism of plant HKT transporters
ChainB
Resolution2.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Y01 B R281 K314 S322 I325 R207 K240 S248 I251
BS02 Y01 B H39 G416 F509 Y513 F519 H18 G329 F422 Y426 F432
BS03 T7X B Y210 S216 G260 L263 Y136 S142 G186 L189
BS04 CLR B I199 L206 L264 F279 F286 I125 L132 L190 F205 F212
Gene Ontology
Molecular Function
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0015081 sodium ion transmembrane transporter activity
GO:0015293 symporter activity
Biological Process
GO:0006812 monoatomic cation transport
GO:0006813 potassium ion transport
GO:0006814 sodium ion transport
GO:0030001 metal ion transport
GO:0035725 sodium ion transmembrane transport
GO:0055075 potassium ion homeostasis
GO:0055085 transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0005886 plasma membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:8k66, PDBe:8k66, PDBj:8k66
PDBsum8k66
PubMed38570642
UniProtQ0D9S3|HKT21_ORYSJ Cation transporter HKT2;1 (Gene Name=HKT2;1)

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