Structure of PDB 8k5n Chain B

Receptor sequence
>8k5nB (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQF
VHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMIS
YGGADYKRITVKVNAP
3D structure
PDB8k5n Discovery of Novel PD-L1 Inhibitors That Induce the Dimerization, Internalization, and Degradation of PD-L1 Based on the Fragment Coupling Strategy.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 I7M B T20 Y56 Q66 M115 I116 S117 A121 D122 Y123 K124 T3 Y39 Q49 M98 I99 S100 A104 D105 Y106 K107
External links
PDB RCSB:8k5n, PDBe:8k5n, PDBj:8k5n
PDBsum8k5n
PubMed38109261
UniProtQ9NZQ7|PD1L1_HUMAN Programmed cell death 1 ligand 1 (Gene Name=CD274)

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