Structure of PDB 8k3u Chain B

Receptor sequence
>8k3uB (length=597) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
FMRYQAVTCEPNQLVRQLKYLTPRETELMLVVTMYNEDHILLGRTLKGIM
DNVKYMVKKKNSSTWGPDAWKKIVVCIISDGRSKINERSLALLSSLGCYA
MHVYEHTTMINITNISESEVSLECPIQLLFCLKEQNQKKINSHRWAFEGF
AELLRPNIVTLLDAGTMPGKDSIYQLWREFRNPNVGGACGEIRTDLGKRF
VKLLNPLVASQNFEYKMSNILDKTTESNFGFITVLPGAFSAYRFEAVRGQ
PLQKYFYGEIMENEGFHFFSSNMYLAEDRILCFEVVTKKNCNWILKYCRS
SYASTDVPERVPEFILQRRRWLNGSFFASVYSFCHFYRVWSSGHNIGRKL
LLTVEFFYLFFNTLISWFSLSSFFLVFRILTVSIALAYHSAFNVLSVIFL
WLYGICTLSTFILSLGNKPKSTEKFYVLTCVIFAVMMIYMIFCSIFMSVK
SIVISLGSTYCLYLISSIIYLQPWHMLTSFIQYILLSPSYINVLNIYAFC
NVHDLSWYDEKKTGYYANVRSLVIIFWVITNFIIVAVLETGGIADYIAMK
SISTAEIPLMTSKASIYFNVILWLVALSALIRFIGCSIYMIVRFFKK
3D structure
PDB8k3u Structure, catalysis, chitin transport, and selective inhibition of chitin synthase
ChainB
Resolution3.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.16: chitin synthase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 UDP B T453 M454 Y455 Q756 R759 T33 M34 Y35 Q317 R320
Gene Ontology
Molecular Function
GO:0004100 chitin synthase activity
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0000920 septum digestion after cytokinesis
GO:0006031 chitin biosynthetic process
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane
GO:0030428 cell septum
GO:0045009 chitosome
GO:0071944 cell periphery

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8k3u, PDBe:8k3u, PDBj:8k3u
PDBsum8k3u
PubMed37553334
UniProtP08004|CHS1_YEAST Chitin synthase 1 (Gene Name=CHS1)

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