Structure of PDB 8k1p Chain B

Receptor sequence
>8k1pB (length=213) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
QVPIEIRGLTKHFGSVRALDGLDLTVREGEVHGFLGPNGAGKSTTLRILL
GLVKADGGSVRLLGGDPWTDAVDLHRHIAYVPGDVTLWPSLTGGETIDLL
ARMRGGIDNARRAELIERFGLDPTKKARTYSKGNRQKVSLISALSSHATL
LLLDEPSSGLDPLMENVFQQCIGEARQRGVTVLLSSHILAETEALCEKVT
IIRAGKTVESGSL
3D structure
PDB8k1p mycobacterial efflux pump, ADP+vanadate bound state
ChainB
Resolution3.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP B F19 N44 G45 A46 G47 K48 S49 T50 F13 N38 G39 A40 G41 K42 S43 T44
BS02 ATP B T135 S137 T129 S131
Gene Ontology
Biological Process
GO:0046677 response to antibiotic
Cellular Component
GO:0005886 plasma membrane

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8k1p, PDBe:8k1p, PDBj:8k1p
PDBsum8k1p
PubMed
UniProtO86311|MEATP_MYCTU Multidrug efflux system ATP-binding protein Rv1218c (Gene Name=Rv1218c)

[Back to BioLiP]