Structure of PDB 8k1o Chain B

Receptor sequence
>8k1oB (length=215) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
NHQVPIEIRGLTKHFGSVRALDGLDLTVREGEVHGFLGPNGAGKSTTLRI
LLGLVKADGGSVRLLGGDPWTDAVDLHRHIAYVPGDVTLWPSLTGGETID
LLARMRGGIDNARRAELIERFGLDPTKKARTYSKGNRQKVSLISALSSHA
TLLLLDEPSSGLDPLMENVFQQCIGEARQRGVTVLLSSHILAETEALCEK
VTIIRAGKTVESGSL
3D structure
PDB8k1o mycobacterial efflux pump, AMPPNP bound state
ChainB
Resolution2.9 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ANP B N44 G47 K48 S49 T50 N40 G43 K44 S45 T46
BS02 ANP B T135 S137 T131 S133
Gene Ontology
Biological Process
GO:0046677 response to antibiotic
Cellular Component
GO:0005886 plasma membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8k1o, PDBe:8k1o, PDBj:8k1o
PDBsum8k1o
PubMed
UniProtO86311|MEATP_MYCTU Multidrug efflux system ATP-binding protein Rv1218c (Gene Name=Rv1218c)

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