Structure of PDB 8jxi Chain B

Receptor sequence
>8jxiB (length=148) Species: 10116 (Rattus norvegicus) [Search protein sequence]
DWKCDNDNDCGDGSDELPTVCAFHTCRSTAFTCGNGRCVPYHYRCDYYND
CGDNSDEAGCLFRNCNSTTEFTCSNGRCIPLSYVCNGINNCHDNDTSDEK
NCPPHTCPPDFTKCQTTNICVPRAFLCDGDNDCGDGSDENPIYCASHT
3D structure
PDB8jxi Cryo-EM structures elucidate the multiligand receptor nature of megalin.
ChainB
Resolution3.4 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B W2718 D2721 D2723 D2725 D2731 E2732 W2 D5 D7 D9 D15 E16
BS02 CA B Y2759 D2762 Y2764 D2766 D2772 E2773 Y43 D46 Y48 D50 D56 E57
BS03 CA B Y2799 V2800 N2802 I2804 N2806 D2814 E2815 Y83 V84 N86 I88 N90 D98 E99
BS04 CA B F2841 D2844 D2846 D2848 D2854 E2855 F125 D128 D130 D132 D138 E139
External links
PDB RCSB:8jxi, PDBe:8jxi, PDBj:8jxi
PDBsum8jxi
PubMed38771880
UniProtP98158|LRP2_RAT Low-density lipoprotein receptor-related protein 2 (Gene Name=Lrp2)

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