Structure of PDB 8jxd Chain B

Receptor sequence
>8jxdB (length=156) Species: 10116 (Rattus norvegicus) [Search protein sequence]
ECGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEIGCPPRSCESGLFLCPA
EGTCIPSSWVCDEDKDCSDGADEQQNCAPRECSESEFRCADQQCIPSRWV
CDQENDCGDNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDAS
DESACP
3D structure
PDB8jxd Cryo-EM structures elucidate the multiligand receptor nature of megalin.
ChainB
Resolution3.3 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B W45 D48 T50 D52 D58 E59 W19 D22 T24 D26 D32 E33
BS02 CA B W85 V86 C87 D88 D92 D98 E99 W59 V60 C61 D62 D66 D72 E73
BS03 CA B W3778 D3781 E3783 D3785 D3791 W99 D102 E104 D106 D112
BS04 CA B L3817 A3818 D3820 R3822 D3824 D3830 E3831 L138 A139 D141 R143 D145 D151 E152
External links
PDB RCSB:8jxd, PDBe:8jxd, PDBj:8jxd
PDBsum8jxd
PubMed38771880
UniProtP98158|LRP2_RAT Low-density lipoprotein receptor-related protein 2 (Gene Name=Lrp2)

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