Structure of PDB 8jqz Chain B

Receptor sequence
>8jqzB (length=374) Species: 57486 (Mus musculus molossinus) [Search protein sequence]
KASSLTEFFKNFKMESKIISKETIDSIQSCIQEGDIQKVISIINAALTDI
EKAPLNIAVTGETGAGKSTFINALRGIGHEESEMDRKKYTHPKFPNVTIW
DLPGVFKPEEYLKKMKFQEYDFFLIISSARFREAQLAEAIKKMKKKFYFV
RTKIDSDLWNEKKAKPSSYNREKILEAIRSDCVKNLQRVFLVSSFEVAQF
DFPSLESTLLEELPAHKRHIFVQCLPTITEPAIDRRRDVLKQTIWLEALK
AGASATIPMMSFFNDDIEEFEKILSHYRACFGLDDESLENMAKEWSMSVE
ELESTIKSPHLLSSEPNESVADKLVKTMEKIFAVTGGFVATGLYFRKSYY
MQNYFLDTVTEDAKVLLKKLEHHH
3D structure
PDB8jqz Structural basis of IRGB10 oligomerization by GTP hydrolysis.
ChainB
Resolution3.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP B T77 G78 A79 G80 K81 S82 T83 K183 D185 F232 T63 G64 A65 G66 K67 S68 T69 K153 D155 F195
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0016787 hydrolase activity
Biological Process
GO:0006952 defense response
GO:0035458 cellular response to interferon-beta
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8jqz, PDBe:8jqz, PDBj:8jqz
PDBsum8jqz
PubMed37705969
UniProtU5NFV2

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