Structure of PDB 8jnb Chain B

Receptor sequence
>8jnbB (length=81) Species: 9606 (Homo sapiens) [Search protein sequence]
NTIRVFLPNSQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVYRLQEKK
PIGWNTDAAWLIGEELQVEFLDHVPLTTHNF
3D structure
PDB8jnb Small-molecule RAS/RAF-binding Inhibitors Allosterically Disrupt RAF Conformation and Exert Efficacy Against Broad-spectrum RAS-driven Cancers
ChainB
Resolution1.62 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 USX B E94 C95 D132 L136 E39 C40 D72 L76
External links
PDB RCSB:8jnb, PDBe:8jnb, PDBj:8jnb
PDBsum8jnb
PubMed
UniProtP04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase (Gene Name=RAF1);
P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf (Gene Name=BRAF)

[Back to BioLiP]