Structure of PDB 8jig Chain B

Receptor sequence
>8jigB (length=193) Species: 9606 (Homo sapiens) [Search protein sequence]
PSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLA
GGYEDDVDHGNFFTYTGSGGCDQKLTNTNRALALNCFAPINDQEGAEAKD
WRSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVW
RYLLRRDDDEPGPWTKEGKDRIKKLGLTMQYPEGYLEALANAH
3D structure
PDB8jig A Novel UHRF1-Targeted Compound
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8JA B N474 W527 R528 R581 R582 N61 W101 R102 R155 R156
External links
PDB RCSB:8jig, PDBe:8jig, PDBj:8jig
PDBsum8jig
PubMed
UniProtQ96T88|UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (Gene Name=UHRF1)

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