Structure of PDB 8jfc Chain B |
>8jfcB (length=531) Species: 5833 (Plasmodium falciparum) [Search protein sequence] |
QVCDVFDIYAICACCKVESNEVFNNYTFRGLGNKGVLPWKCISLDMKYFR AVTTYVNESKYEKLKYKRCKYLNKETVDLQNVVVMGRTNWESIPKKFKPL SNRINVILSRTLKKEDFDEDVYIINKVEDLIVLLGKLNYYKCFILGGSVV YQEFLEKKLIKKIYFTRINSTYECDVFFPEINENEYQIISVSDVYTSNNT TLDFIIYKKTNDDEEEDDFVYFNFNKENKNSIHPNDFQIYNSLKYKYHPE YQYLNIIYDIMMNGNKQSDRTGVGVLSKFGYIMKFDLSQYFPLLTTKKLF LRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFHREVND LGPIYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLC AWNVKDLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASY SIFTHMIAQVCNLQPAQFIHVLGNAHVYNNHIDSLKIQLNRIPYPFPTLK LNPDIKNIEDFTISDFTIQNYVHHEKISMDM |
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PDB | 8jfc Discovery of rigid biphenyl Plasmodium falciparum DHFR inhibitors using a fragment linking strategy. |
Chain | B |
Resolution | 2.3 Å |
3D structure |
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Enzyme Commision number |
1.5.1.3: dihydrofolate reductase. 2.1.1.45: thymidylate synthase. |
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