Structure of PDB 8jbf Chain B

Receptor sequence
>8jbfB (length=282) Species: 9606 (Homo sapiens) [Search protein sequence]
NQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLV
NLAFSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYS
MTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKTK
VMPGRTLCFVQWPEGPKQHFTYHIIVIILVYCFPLLIMGITYTIVGITLW
GEQLKAKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQV
YLASFWLAMSSTMYNPIIYCCLNKRFRAGFKR
3D structure
PDB8jbf Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists.
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B F78 Y145 L232 F234 Q236 H248 Y315 F319 N329 R330 Y338 F3 Y70 L157 F159 Q161 H173 Y228 F232 N242 R243 Y251
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004995 tachykinin receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8jbf, PDBe:8jbf, PDBj:8jbf
PDBsum8jbf
PubMed37391393
UniProtP29371|NK3R_HUMAN Neuromedin-K receptor (Gene Name=TACR3)

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