Structure of PDB 8j8h Chain B

Receptor sequence
>8j8hB (length=286) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence]
NVPKKPPDHSKSNLLYQQIFLHDKQAIEKEETYDSNWFPIISFPNELRFH
RYDWRLPKQFDVRTLAFPAIRYKEYLCTFAWEYDFIHQLPKTETYNGQES
IRISTSDILSGRYDTDFIRNYECQRLIVQLINKAFELRMKDKNVREYQMS
KTFAYWIEKGKLEKDKFEKIKLVGKQKNKYWHFGISAAGKLYPSPVLMVS
SHIIFTMDGINLIKSKSIQHSSRRKQGKNWWNDKWREKLLAFIRFLSDDQ
NAIYLNVGSEEKILISNKPLKFFGKMSYVTPSEVTL
3D structure
PDB8j8h Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.
ChainB
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B K211 R263 M287 S288 K289 K354 H358 R362 K73 R125 M149 S150 K151 K216 H220 R224
BS02 dna B R201 R263 V266 Q267 N270 K328 H358 K363 W369 L424 R63 R125 V128 Q129 N132 K190 H220 K225 W231 L286
Gene Ontology
Biological Process
GO:0007165 signal transduction

View graph for
Biological Process
External links
PDB RCSB:8j8h, PDBe:8j8h, PDBj:8j8h
PDBsum8j8h
PubMed37932527
UniProtA0A1I7NFG5

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