Structure of PDB 8j86 Chain B

Receptor sequence
>8j86B (length=209) Species: 10244 (Monkeypox virus) [Search protein sequence]
ISHAPITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPL
RNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKG
YNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYC
LGKTDFSNIRAKLESPVTTIVGYHPAARDHQFEKDRSFEIINVLLELDNK
TPINWAQGF
3D structure
PDB8j86 Structure of DNA replication machinery from human monkeypox virus in complex with a DNA duplex
ChainB
Resolution3.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.27: uracil-DNA glycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B T130 K160 H181 T123 K153 H174
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0016787 hydrolase activity
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:8j86, PDBe:8j86, PDBj:8j86
PDBsum8j86
PubMed38735603
UniProtM1LL92|UNG_MONPV Uracil-DNA glycosylase (Gene Name=OPG116)

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