Structure of PDB 8j4f Chain B

Receptor sequence
>8j4fB (length=173) Species: 9606 (Homo sapiens) [Search protein sequence]
GCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVK
ILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDY
ECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVV
LTIWLVAEMIYCYKKIAAATETA
3D structure
PDB8j4f Structural mapping of Na v 1.7 antagonists.
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LPE B W173 L174 E177 C181 W154 L155 E158 C162
Gene Ontology
Molecular Function
GO:0017080 sodium channel regulator activity
Biological Process
GO:0006814 sodium ion transport
Cellular Component
GO:0001518 voltage-gated sodium channel complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8j4f, PDBe:8j4f, PDBj:8j4f
PDBsum8j4f
PubMed37270609
UniProtQ07699|SCN1B_HUMAN Sodium channel subunit beta-1 (Gene Name=SCN1B)

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