Structure of PDB 8j3s Chain B

Receptor sequence
>8j3sB (length=215) Species: 10359 (Human betaherpesvirus 5) [Search protein sequence]
TPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAVALPLNINHDDTAVVG
HVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKV
VEFLSGSYAGLSLSSPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFPDLT
AADRDGLRAQWQSTAVDASGDPFRSDSYGLLGNSVDALYIRERLPKLRYD
KQLVGVTERESYVKA
3D structure
PDB8j3s Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of beta-Herpesvirus Proteases
ChainB
Resolution3.09 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.97: assemblin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B N62 H63 S132 L133 S134 S135 H157 C161 V163 G164 R165 D227 I231 K237 N42 H43 S112 L113 S114 S115 H119 C123 V125 G126 R127 D186 I190 K196
BS02 peptide B L106 R109 L86 R89
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8j3s, PDBe:8j3s, PDBj:8j3s
PDBsum8j3s
PubMed37974946
UniProtP16753|SCAF_HCMVA Capsid scaffolding protein (Gene Name=UL80)

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