Structure of PDB 8j3o Chain B

Receptor sequence
>8j3oB (length=373) Species: 573826 (Candida dubliniensis CD36) [Search protein sequence]
GKPKVLMALYSGGKHAKEEPRLLGTVENELGIRKLVEEHGYELVTTADKD
PFPSSTFDKNLPDAEIIITTPFFPAYVTKERIAKAPKLKLCVTAGVGSDH
YDLNALNERGIAVLEVTGSNVQSVAEHAIMTMLILLRNYGEGHAQATQGT
WDIAAVAKDEFDMEDKVFATIGAGRIGYRILERLIAFNPKKLLYYDYQPL
PEEAINKLNAASKLFNGVDNIIERVENLEDLVSQADVVTLNCPLYEKSKG
MFNKELISKMKKGSYVINTARGALTDPQAIADAVNSGHIAYGGDVWPVQP
APKDMPWRTMHNPYGKDYGNAMTVHVSGTSLDAQARYANGVKQILTEYFD
KTYKYRPQDVICIDGHYATKAYG
3D structure
PDB8j3o Engineering a Formate Dehydrogenase for NADPH Regeneration.
ChainB
Resolution2.65 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.17.1.9: formate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAI B P72 V97 G98 N121 V125 G175 R176 I177 D197 Y198 C243 P244 Y246 T270 Y373 P71 V96 G97 N120 V124 G174 R175 I176 D196 Y197 C242 P243 Y245 T269 Y372
BS02 MG B L136 L137 D160 Y266 L135 L136 D159 Y265
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008863 formate dehydrogenase (NAD+) activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0046872 metal ion binding
GO:0051287 NAD binding
Biological Process
GO:0019752 carboxylic acid metabolic process
GO:0042183 formate catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8j3o, PDBe:8j3o, PDBj:8j3o
PDBsum8j3o
PubMed37455264
UniProtB9WHT3

[Back to BioLiP]