Structure of PDB 8j3a Chain B

Receptor sequence
>8j3aB (length=290) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search protein sequence]
FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICCEDLLIRK
SNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQT
FSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCY
MHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAA
VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAV
LDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCS
3D structure
PDB8j3a Crystal structure of SARS-Cov-2 main protease Y54C mutant in complex with PF00835231
ChainB
Resolution1.91 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.50: mRNA guanylyltransferase.
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.4.22.69: SARS coronavirus main proteinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 V2M B H41 F140 L141 N142 C145 H163 H164 M165 E166 Q189 T190 A191 H39 F129 L130 N131 C134 H152 H153 M154 E155 Q178 T179 A180
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0019082 viral protein processing

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Molecular Function
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Biological Process
External links
PDB RCSB:8j3a, PDBe:8j3a, PDBj:8j3a
PDBsum8j3a
PubMed
UniProtP0DTD1|R1AB_SARS2 Replicase polyprotein 1ab (Gene Name=rep)

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