Structure of PDB 8j0g Chain B

Receptor sequence
>8j0gB (length=274) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
RAFAKDVKRIVVKVGTAVVTGKGGRLALGRLGAICEQLAELNSDGFEVIL
VSSGAVGLGRQRLRYRQLVNSSFADLQKPQMELDGKACAGVGQSSLMAYY
ETMFDQLDVTVAQMLVTDSSFRDKDFRKQLSETVKAMLRMRVIPVFNEND
AISTRRTGIFWDNDSLAALLSLELKADLLILLSDVEGLYTGPPSDSTSKL
IHTFIKEKHQDEITFGEKSKLGRGGMTAKVKAAVNAAYGGVPVIITSGYA
AENISKVLRGLRVGTLFHQDAHLW
3D structure
PDB8j0g GK monomer complexes with glutamate and ATP
ChainB
Resolution3.7 Å
3D
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Enzymatic activity
Enzyme Commision number 1.2.1.41: glutamate-5-semialdehyde dehydrogenase.
2.7.2.11: glutamate 5-kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y72 L75 V76 F80 Y65 L68 V69 F73
BS02 MG B R236 G237 G238 R223 G224 G225
BS03 GGL B A62 N154 D157 N176 R236 A55 N147 D150 N163 R223
BS04 ATP B K20 G22 T23 A24 V198 G204 P206 F228 R236 G238 M239 K242 K13 G15 T16 A17 V185 G191 P193 F215 R223 G225 M226 K229
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004349 glutamate 5-kinase activity
GO:0004350 glutamate-5-semialdehyde dehydrogenase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Biological Process
GO:0006561 proline biosynthetic process
GO:0009084 glutamine family amino acid biosynthetic process
GO:0009555 pollen development
GO:0009793 embryo development ending in seed dormancy
GO:0016310 phosphorylation
GO:0055129 L-proline biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0009506 plasmodesma
GO:0009507 chloroplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8j0g, PDBe:8j0g, PDBj:8j0g
PDBsum8j0g
PubMed
UniProtP54888|P5CS2_ARATH Delta-1-pyrroline-5-carboxylate synthase B (Gene Name=P5CSB)

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