Structure of PDB 8j0f Chain B

Receptor sequence
>8j0fB (length=270) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
IDRSRAFAKDVKRIVVKVGTAVVTGKGGRLALGRLGAICEQLAELNSDGF
EVILVSSGAVGLGRQRLRYRQLVNSSFADLQKPQMELDGKACAGVGQSSL
MAYYETMFDQLDVTVAQMLVTDSSFRDKDFRKQLSETVKAMLRMRVIPVF
NENDAISTRWDNDSLAALLSLELKADLLILLSDVEGLYTGPPSDSTSKLI
HTFIKEKHQDEITFGERGGMTAKVKAAVNAAYGGVPVIITSGYAAENISK
VLRGLRVGTLFHQDAHLWAP
3D structure
PDB8j0f GK tetramer with adjacent hooks at reaction state
ChainB
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.2.1.41: glutamate-5-semialdehyde dehydrogenase.
2.7.2.11: glutamate 5-kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B V76 N77 S78 S79 F80 A81 V73 N74 S75 S76 F77 A78
BS02 peptide B L75 F80 L83 L72 F77 L80
BS03 ADP B A24 D197 V198 Y202 G204 F228 G238 M239 A21 D183 V184 Y188 G190 F214 G219 M220
BS04 RGP B K20 T23 S60 D157 N176 R236 K17 T20 S57 D154 N162 R217
BS05 MG B R236 G237 G238 R217 G218 G219
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004349 glutamate 5-kinase activity
GO:0004350 glutamate-5-semialdehyde dehydrogenase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Biological Process
GO:0006561 proline biosynthetic process
GO:0009084 glutamine family amino acid biosynthetic process
GO:0009555 pollen development
GO:0009793 embryo development ending in seed dormancy
GO:0016310 phosphorylation
GO:0055129 L-proline biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0009506 plasmodesma
GO:0009507 chloroplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8j0f, PDBe:8j0f, PDBj:8j0f
PDBsum8j0f
PubMed38740943
UniProtP54888|P5CS2_ARATH Delta-1-pyrroline-5-carboxylate synthase B (Gene Name=P5CSB)

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