Structure of PDB 8ir2 Chain B

Receptor sequence
>8ir2B (length=198) Species: 9606 (Homo sapiens) [Search protein sequence]
TPKHIIQMTGFKMEEKEALVKLLLKLDCTFIKSEKYKNCTHLIAERLCKS
EKFLAACAAGKWILTKDYIIHSAKSGRWLDETTYEWGYKIEKDSRYSPQM
QSAPKRWREELKRTGAPGAFHRWKVVLLVRTDKRSDSLIRVLEAGKANVI
LPKSSPSGITHVIASNARIKAEKEKDNFKAPFYPIQYLGDFLLEKLEH
3D structure
PDB8ir2 Structural insights into Rad18 targeting by the SLF1 BRCT domains.
ChainB
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B T13 G14 M17 K20 K36 E38 R50 K53 S54 K56 L58 Q190 T9 G10 M13 K16 K32 E34 R46 K49 S50 K52 L54 Q186
Gene Ontology
Biological Process
GO:2000781 positive regulation of double-strand break repair

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Biological Process
External links
PDB RCSB:8ir2, PDBe:8ir2, PDBj:8ir2
PDBsum8ir2
PubMed37748650
UniProtQ9BQI6|SLF1_HUMAN SMC5-SMC6 complex localization factor protein 1 (Gene Name=SLF1)

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