Structure of PDB 8io9 Chain B

Receptor sequence

>8io9B (length=788) Species: 1140 (Synechococcus elongatus PCC 7942 = FACHB-805)

DIATLSPNEQAAIDAWWRAANYLSVGQIYLRDNPLLQEPLRPEHIKQRLL
GHWGSDPGLSFVYVHLNRLIRRLDLNLIYVTGPGHGAPALLANAWLEGTY
SEVYPNCQQSTAGLQQFFKQFSFPGGIGSHCTPETPGSIHEGGELGYSLS
HAFGAALDNPDLIVACVIGDGEAETGPLATSWHSNKFLNPAQDGAVLPIL
HLNGYKIANPTLLSRISHEELRSLFIGYGYEPFFVEGNDPAILHGVMAST
LATCVQKIQAIQAAARSGESSDRPMWPMIVLRTPKGWTGPATIKGHVVEG
SWRSHQVPMADVLTNPEHLQLLEDWLRSYRPEELFDASGAPVAELQAIAP
IGDRRMSANPVTNGGLLRRALTLPDFRDQAVSVPAPGKSRADSTRPLGQF
LREVIRHNPDNFRLFGPDETASNRLDAVYEVTSKVWLGDRIPEDEDGGHL
SDRGRVMEILSEHTLEGWLEAYLLTGRHGFFATYEAFAHVIDSMVNQHAK
WLDVSKREVDWRAPVSSLNILLSSTVWRQDHNGFSHQDPGFIDLVTNKSA
RVTRIYLPPDANCLLSVADHCLRSTDYINVIVADKQSHLQYLDAEAAARH
CAKGIGIWDWASNDQGASPDVVIASCGDVVTLEALAATALLREHFPDLKI
RFVNVVDLFRLQPDTEHPHGLSDRDFDSLFTVDKPIIFNFHGYPWLIHKL
AYRRHNHNNLHVRGYKEVGNINTPLELAIRNQVDRFNLAIDVIDRVPHLR
DRGAHVKEWLKDQIHDHIQYAYQEGIDRPEINQWQWPF

3D structure

• PDB: 8io9 An ATP-sensitive phosphoketolase regulates carbon fixation in cyanobacteria.
• Chain: B
• Resolution: 2.36 Å

Enzymatic activity

• Enzyme Commision number: 4.1.2.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ANP	B	Y710 R711	Y702 R703
BS02	TPP	B	L468 F495	L460 F487
BS03	ANP	B	H706 V720 R721 R753	H698 V712 R713 R745
BS04	TPP	B	S63 H93 L153 G177 D178 G179 N211 Y213 I215 K293	S55 H85 L145 G169 D170 G171 N203 Y205 I207 K285
BS05	MG	B	D178 N211 Y213	D170 N203 Y205

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0016829 lyase activity
• GO:0016832 aldehyde-lyase activity

Biological Process

• GO:0005975 carbohydrate metabolic process

External links

• PDB: RCSB:8io9, PDBe:8io9, PDBj:8io9
• PDBsum: 8io9
• PubMed: 37349485
• UniProt: Q31LF9|PHK_SYNE7 Probable phosphoketolase (Gene Name=Synpcc7942_2080)