Structure of PDB 8ii2 Chain B

Receptor sequence
>8ii2B (length=115) Species: 9606 (Homo sapiens) [Search protein sequence]
CPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSESGELHGLT
TEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAA
LLSPYSYSTTAVVTN
3D structure
PDB8ii2 Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis.
ChainB
Resolution1.798 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B F64 D99 F55 D90
BS02 R75 B K15 L17 A108 L110 S117 T118 K6 L8 A99 L101 S108 T109
External links
PDB RCSB:8ii2, PDBe:8ii2, PDBj:8ii2
PDBsum8ii2
PubMed37311373
UniProtP02766|TTHY_HUMAN Transthyretin (Gene Name=TTR)

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