Structure of PDB 8i87 Chain B

Receptor sequence

>8i87B (length=467) Species: 429344 (Maribacter polysiphoniae) [Search protein sequence]

MKELIYIEEPKILFAHGQKCTDARDGLALFGPLNNLYGIKSGVIGTKQGL
KIFRDYLDHIQKPIYNSNSITRPMFPGFEAVFDCKWESTGITFKEVTNED
IGKFLYNSSTHKRTYDLVSLFIDKIISANKNEDENVDVWFVIVPDEIYKY
CRPNSVLPKENYDAQFHDQFKARLLKHTIPTQIFRESTLAWRDFKNAFGL
PIRDFSKIEGHLAWTISTAAFYKAGGKPWKLSDVRNGVCYLGLVYKKVEK
SKNPRNACCAAQMFLDNGDGTVFKGEVGPWYNPKNGQYHLEPKEAKALLS
QSLQSYKEQIGEYPKEVFIHAKTRFNHQEWDAFLEVTPKETNLVGVTISK
TKPLKLYKTEGDYTILRGNAYVVNERSAFLWTVGYVPKIQTALSMEVPNP
LFIEINKGEADIKQVLKDILSLTKLNYNACIFADGEPVTLRFADKIGEIL
TASTDIKTPPLAFKYYI

3D structure

PDB

8i87 Structural insights into mechanisms of Argonaute protein-associated NADase activation in bacterial immunity.

Chain

Resolution

3.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	B	Y148 Q205 H207 K211 Q222 I223 F224 R225 T228 F245 H251 L252 T255 K324 N325 K395 E436 N468 A469 G475 R481 I507	Y148 Q165 H167 K171 Q182 I183 F184 R185 T188 F205 H211 L212 T215 K284 N285 K355 E396 N428 A429 G435 R441 I467
BS02	dna	B	T71 R72 N154 I248 H251 K286 K287 Y328 T363 R364	T71 R72 N154 I208 H211 K246 K247 Y288 T323 R324
BS03	MG	B	N468 I507	N428 I467

Gene Ontology

	Molecular Function
GO:0003676	nucleic acid binding

View graph for
Molecular Function

External links

PDB	RCSB:8i87, PDBe:8i87, PDBj:8i87
PDBsum	8i87
PubMed	37311833
UniProt	A0A316E3U6

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