Structure of PDB 8hs4 Chain B

Receptor sequence
>8hs4B (length=237) Species: 224914 (Brucella melitensis bv. 1 str. 16M) [Search protein sequence]
SPFHLNDAVAIVTGAAAGIGRAIAGTFAKAGASVVVTDLKSEGAEAVAAA
IRQAGGKAIGLECNVTDEQHREAVIKAALDQFGKITVLVNNAGGGGPKPF
DMPMSDFEWAFKLNLFSLFRLSQLAAPHMQKAGGGAILNISSMAGENTNV
RMASYGSSKAAVNHLTRNIAFDVGPMGIRVNAIAPGAIKERAILKHTPLG
RLGEAQDIANAALFLCSPAAAWISGQVLTVSGGGVQE
3D structure
PDB8hs4 Structure of 7-alpha-hydroxysteroid dehydrogenase
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.159: 7alpha-hydroxysteroid dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B G67 G71 I72 D91 L92 C116 N117 V118 N144 A145 I193 S195 Y208 K212 P238 G239 E302 G14 G18 I19 D38 L39 C63 N64 V65 N91 A92 I140 S142 Y155 K159 P185 G186 E237
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:8hs4, PDBe:8hs4, PDBj:8hs4
PDBsum8hs4
PubMed
UniProtQ8YIN7

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