Structure of PDB 8hp3 Chain B

Receptor sequence
>8hp3B (length=298) Species: 386414 (Hoylesella timonensis) [Search protein sequence]
KKIRAAIVGYGNIGKFTVEAVEAAEDFELVGIVRRQGAENKPAELAPYKV
VQDIKELEGVDVAILATPSRSCKEYAEKILPLGINTVDSFDIHTDIVDYR
SALMPLCKEHHAVSIISAGWDPGSDSVVRTLMQSLAPKGLSYTNFGPGMS
MGHSVCARSKKGVKNALSMTIPLGEGIHRRMVYVELEEGATLDEVTKEIK
ADPYFAHDETHVMAVDSVDAVKDMGHGVHLVRKGVSGKTQNQRMEFSMSI
NNPALTAQVLVNVARASMHQQPGCYTMVEIPVIDLLAGEREDLIKALV
3D structure
PDB8hp3 Rational design of meso-diaminopimelate dehydrogenase to enhance reductive amination activity for efficient production of D-HPG
ChainB
Resolution3.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.4.1.16: diaminopimelate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NDP B G10 Y11 G12 N13 I14 R35 R36 A67 T68 P69 S70 Y76 S90 D92 D122 N253 G9 Y10 G11 N12 I13 R34 R35 A66 T67 P68 S69 Y75 S89 D91 D121 N252
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0047850 diaminopimelate dehydrogenase activity
Biological Process
GO:0009085 lysine biosynthetic process
GO:0009089 lysine biosynthetic process via diaminopimelate
GO:0019877 diaminopimelate biosynthetic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8hp3, PDBe:8hp3, PDBj:8hp3
PDBsum8hp3
PubMed37070978
UniProtA0A2K0XCZ3

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