Structure of PDB 8hkq Chain B

Receptor sequence
>8hkqB (length=902) Species: 9606 (Homo sapiens) [Search protein sequence]
RSSLRIRLFNFSLKLLTCLLYIVRVLLDDPALGIGCWGCPKQNYSFNDSS
SEINWAPILWVERKMTLWAIQVIVAIISFLETMLLIYLSYKGNIWEQIFR
VSFVLEMINTLPFIITIFWPPLRNLFIPVFLNCWLAKHALENMINDFHRS
AMFNQVLILFCTLLCLVFTGTCGIQHLERAGENLSLLTSFYFCIVTFSTV
GYGDVTPKIWPSQLLVVIMICVALVVLPLQFEELVYLWMERQKQTEKHVV
LCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPLW
SQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRA
WAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCICPA
TSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFREY
EGKSFTYAAFHAHKKYGVCLIGLKREDNKSILLNPGPRHILAASDTCFYI
NITKEENSAFIFKQEEKRKIAPVLELAVEYVKGYPPNSPYIGSSPTLCHL
LPVKAPFCCLRLDKGCKHNSYEDAKAYGFKNKLIIVSAETAGNGLYNFIV
PLRAYYRSRKELNPIVLLLDNKPDHHFLEAICCFPMVYYMEGSVDNLDSL
LQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSITT
ELTHPSNMRFMQFRAKDSYSLALSKLEKRERENGSNLAFMFRLPFAAGRV
FSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEGDLWI
RTYGRLFQKLCSSSAEIPIGIYRTESHVFAAEWISQQRLSLYRRSERQEL
SELVKNRMKHLGLPTTGYDHQNTLSYVLINPPPDTRLEPSDIVYLIRSDP
LA
3D structure
PDB8hkq Structural basis of human Slo2.2 channel gating and modulation.
ChainB
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LQ9 B G285 C308 T311 F312 T314 M334 I335 L339 G170 C193 T196 F197 T199 M219 I220 L224
BS02 ZN B C778 C785 H787 C559 C566 H568
Gene Ontology
Biological Process
GO:0006813 potassium ion transport
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:8hkq, PDBe:8hkq, PDBj:8hkq
PDBsum8hkq
PubMed37494189
UniProtQ5JUK3|KCNT1_HUMAN Potassium channel subfamily T member 1 (Gene Name=KCNT1)

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