Structure of PDB 8hke Chain B

Receptor sequence
>8hkeB (length=647) Species: 9606 (Homo sapiens) [Search protein sequence]
SVLVFEISSKMKMIEKKLEANTVHVLRLELDQSFILDLTKVAAEIVDSSK
YSKEDGVILEVTVSNGRDSFLLKLPTVYPNLKLYTDGKLLNPLVEQDFHF
HQNLIVTVQSRLNADIDYRLHVTHLDRAQYDFLKFKTGQTTKTLSNQKLT
FVKPIGFFLNCSEQNISQFHVTLYSEDDICANLITVPANESIYDRSVISD
KTHNRRVLSFTKRADIFFTETEISMFKSFRIFVFIAPDDSGCSTNTSRKS
FNEKKKISFEFKKLENQSYAVPTALMMIFLTTPCLLFLPIVINIIKNSRS
LHGQMLQYPVAIILPVLMHTAIEFHKWTTSTMANRDEMCFHNHACARPLG
ELRAWNNIITNIGYTLYGAIFIVLSICRRGSHVFGTYECTLLDVTIGVFM
VLQSIASATYHICPSDVAFQFDTPCIQVICGLLMVRQWFVRHESPSPAYT
NILLVGVVSLNFLISAFSKTSYVRFIIAVIHVIVVGSICLAKERSLGSEK
LKTRFFIMAFSMGNFAAIVMYLTLSAFHLNQIATYCFIINCIMYLMYYGC
MKVLHSERITSKAKLCGALSLLAWAVAGFFFFQDDTDWTRSAAASRALNK
PCLLLGFFGSHDLWHIFGALAGLFTFIFVSFVDDDLINTRKTSINIF
3D structure
PDB8hke dsRNA transporter
ChainB
Resolution3.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B H540 D551 H740 H744 H411 D422 H611 H615
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:8hke, PDBe:8hke, PDBj:8hke
PDBsum8hke
PubMed38664565
UniProtQ9GZC8|SID1_CAEEL Systemic RNA interference defective protein 1 (Gene Name=sid-1)

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