Structure of PDB 8hd8 Chain B

Receptor sequence
>8hd8B (length=137) Species: 9606 (Homo sapiens) [Search protein sequence]
CSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYS
SQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVSTSFMKLNTSA
GNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNDDDD
3D structure
PDB8hd8 Crystal structure of TMPRSS2 in complex with 212-148
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.122: transmembrane protease serine 2.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B N131 D134 V136 H138 D144 E145 N19 D22 V24 H26 D32 E33
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:8hd8, PDBe:8hd8, PDBj:8hd8
PDBsum8hd8
PubMed37990007
UniProtO15393|TMPS2_HUMAN Transmembrane protease serine 2 (Gene Name=TMPRSS2)

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