Structure of PDB 8haq Chain B

Receptor sequence
>8haqB (length=243) Species: 9606 (Homo sapiens) [Search protein sequence]
KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLAQVMKKLRH
EKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQ
IASGMAYVERMNYVHRDLRAANILVGENLVCKVADPIKWTAPEAALYGRF
TIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPE
SLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGEN
3D structure
PDB8haq The complex of Src with GW8510
ChainB
Resolution2.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 L1N B V271 L273 V281 A293 Y340 M341 G344 L393 V15 L17 V25 A37 Y71 M72 G75 L124
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8haq, PDBe:8haq, PDBj:8haq
PDBsum8haq
PubMed
UniProtP12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

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