Structure of PDB 8h7a Chain B

Receptor sequence
>8h7aB (length=77) Species: 9606 (Homo sapiens) [Search protein sequence]
VKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQL
ELSVKDGTILKVSNKGLNSYKDPDNPG
3D structure
PDB8h7a The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.
ChainB
Resolution1.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B K24 Q25 R26 K23 Q24 R25
BS02 dna B Q23 K24 Q25 Q22 K23 Q24
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:8h7a, PDBe:8h7a, PDBj:8h7a
PDBsum8h7a
PubMed36537216
UniProtQ92794|KAT6A_HUMAN Histone acetyltransferase KAT6A (Gene Name=KAT6A)

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