Structure of PDB 8h6u Chain B

Receptor sequence
>8h6uB (length=337) Species: 40559 (Botrytis cinerea) [Search protein sequence]
KRPPFVRVPDLFGSIMSTKPVVNPNYFAAKARGDRWIARVMNFNKAVAAR
NSKVDLCFLASMWAPDAPEDRLVMMLDWNHWVFLFDDQFDEGHLKEDPAA
AAEEVKQTIAIMGGNAPRYTAESNPIRYVFQQCWDRLKAVSSQEMQQRWI
DQHKRYFDQLLVQVDQQVGGENFTRDVEAYMDLRRGTIGVYPAISLSEYG
AGVNVPQHVYDHPSLQECMKVSADLVTLVNDVLSYRKDLELGVDHNLMSL
LMQRDNLSAQQAVDVIGDMVNECYRRWYLALAELPSYGEKIDYNVMKFVE
ICRAVAQGNLYWSFQTGRYLGPEGHEVHETGIMYLPP
3D structure
PDB8h6u Structural Insights into Three Sesquiterpene Synthases for the Biosynthesis of Tricyclic Sesquiterpenes and Chemical Space Expansion by Structure-Based Mutagenesis.
ChainB
Resolution2.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.3.74: presilphiperfolanol synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D102 D106 D86 D90
BS02 MG B N246 S250 N230 S234
BS03 POP B D106 R200 N246 S250 K253 R334 Y335 D90 R184 N230 S234 K237 R318 Y319
BS04 BTM B W79 F99 D102 I204 G205 A209 W63 F83 D86 I188 G189 A193
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0010334 sesquiterpene synthase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0045338 farnesyl diphosphate metabolic process
GO:0051762 sesquiterpene biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8h6u, PDBe:8h6u, PDBj:8h6u
PDBsum8h6u
PubMed37018048
UniProtQ6WP50|BOT2_BOTFU Presilphiperfolan-8-beta-ol synthase (Gene Name=BOT2)

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