Structure of PDB 8h6d Chain B

Receptor sequence
>8h6dB (length=162) Species: 9606 (Homo sapiens) [Search protein sequence]
GIIEFHVIGNSLNRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKT
LALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKE
YHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATL
MECELNPRIPYT
3D structure
PDB8h6d Molecular Basis of KAT2A Selecting Acyl-CoA Cofactors for Histone Modifications.
ChainB
Resolution3.26 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GRA B Q530 C579 A580 V581 Q586 V587 G589 G591 T592 Y613 D615 G620 Y621 Q30 C79 A80 V81 Q86 V87 G89 G91 T92 Y113 D115 G120 Y121
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups

View graph for
Molecular Function
External links
PDB RCSB:8h6d, PDBe:8h6d, PDBj:8h6d
PDBsum8h6d
PubMed37040526
UniProtQ92830|KAT2A_HUMAN Histone acetyltransferase KAT2A (Gene Name=KAT2A)

[Back to BioLiP]