Structure of PDB 8gzf Chain B

Receptor sequence
>8gzfB (length=266) Species: 9606 (Homo sapiens) [Search protein sequence]
NHQWYVCNREKLCESLQAVFVQSYLDQGTQIFLNNSIEKSGWLFIQLYHS
FVSSVFSLFMSRTSINGLLGRGSMFVFSPDQFQRLLKINPDWKTHRLLDL
GAGDGEVTKIMSPHFEEIYATELSETMIWQLQKKKYRVLGINEWQNTGFQ
YDVISCLNLLDRCDQPLTLLKDIRSVLEPTRGRVILALVLPFHPYVENVG
GKWEKPSEILEIKGQNWEEQVNSLPEVFRKAGFVIEAFTRLPYLCEGDMY
NDYYVLDDAVFVLKPV
3D structure
PDB8gzf Crystal Structure of METTL9-SAH
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH B G153 E174 L175 I193 L209 N210 L211 Y295 G101 E122 L123 I141 L157 N158 L159 Y243
Gene Ontology
Molecular Function
GO:0106370 protein-L-histidine N-pros-methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:8gzf, PDBe:8gzf, PDBj:8gzf
PDBsum8gzf
PubMed37398635
UniProtQ9H1A3|METL9_HUMAN Protein-L-histidine N-pros-methyltransferase (Gene Name=METTL9)

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