Structure of PDB 8grj Chain B

Receptor sequence

>8grjB (length=531) Species: 292 (Burkholderia cepacia)

ADVVVVGSGVAGAIVAHQLAMAGKAVILLEAGPRMPRWEIVERFRNQPDK
MDFMAPYPSSPWAPHPEYGPPNDYLILKGEHKFNSQYIRAVGGTTWHWAA
SAWRFIPNDFKMKSVYGVGRDWPIQYDDLEPYYQRAEEELGVWGPGPEED
LYSPRKQPYPMPPLPLSFNEQTIKTALNNYDPKFHVVTEPVARNSRPYDG
RPTCCGNNNCMPICPIGAMYNGIVHVEKAERAGAKLIENAVVYKLETGPD
KRIVAALYKDKTGAEHRVEGKYFVLAANGIETPKILLMSANRDFPNGVAN
SSDMVGRNLMDHPGTGVSFYASEKLWPGRGPQEMTSLIGFRDGPFRATEA
AKKIHLSNLSRIDQETQKIFKAGKLMKPDELDAQIRDRSARYVQFDCFHE
ILPQPENRIVPSKTATDAIGIPRPEITYAIDDYVKRGAAHTREVYATAAK
VLGGTDVVFNDEFAPNNHITGSTIMGADARDSVVDKDCRTFDHPNLFISS
SATMPTVGTVNVTLTIAALALRMSDTLKKEV

3D structure

• PDB: 8grj X-ray structure of the direct electron transfer-type FAD glucose dehydrogenase catalytic subunit complexed with a hitchhiker protein.
• Chain: B
• Resolution: 2.95 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	B	G15 G17 V18 A19 E38 A39 Q94 R97 T102 H105 W106 A107 S109 M219 V250 A285 N286 E289 I293 N475 N519 T521	G7 G9 V10 A11 E30 A31 Q86 R89 T94 H97 W98 A99 S101 M211 V242 A277 N278 E281 I285 N467 N511 T513
BS02	F3S	B	C212 C213 G214 N215 N217 C218 C222 P339	C204 C205 G206 N207 N209 C210 C214 P331
BS03	LGC	B	M219 E341 H363 N474 N475 H476 N519	M211 E333 H355 N466 N467 H468 N511

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0016491 oxidoreductase activity
• GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
• GO:0046872 metal ion binding
• GO:0050660 flavin adenine dinucleotide binding
• GO:0051538 3 iron, 4 sulfur cluster binding

External links

• PDB: RCSB:8grj, PDBe:8grj, PDBj:8grj
• PDBsum: 8grj
• UniProt: Q8GQE7