BioLiP

Site
#

Ligand

Ligand
chain

Binding residues on receptor
(original residue number in PDB)

Binding residues on receptor
(residue number reindexed from 1)

Binding affinity

BS01

peptide

R7 V8 K10 K11 R25 R103 K107 L166

R2 V3 K5 K6 R20 R98 K102 L161

	Molecular Function
GO:0001664	G protein-coupled receptor binding
GO:0003713	transcription coactivator activity
GO:0004402	histone acetyltransferase activity
GO:0005096	GTPase activator activity
GO:0005102	signaling receptor binding
GO:0005159	insulin-like growth factor receptor binding
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0030276	clathrin binding
GO:0030331	nuclear estrogen receptor binding
GO:0031434	mitogen-activated protein kinase kinase binding
GO:0031625	ubiquitin protein ligase binding
GO:0031691	alpha-1A adrenergic receptor binding
GO:0031692	alpha-1B adrenergic receptor binding
GO:0031701	angiotensin receptor binding
GO:0031762	follicle-stimulating hormone receptor binding
GO:0031896	V2 vasopressin receptor binding
GO:0035612	AP-2 adaptor complex binding
GO:0035615	clathrin adaptor activity
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0044325	transmembrane transporter binding
GO:0045309	protein phosphorylated amino acid binding
GO:0051219	phosphoprotein binding
GO:1990763	arrestin family protein binding

	Biological Process
GO:0001934	positive regulation of protein phosphorylation
GO:0002031	G protein-coupled receptor internalization
GO:0002092	positive regulation of receptor internalization
GO:0006355	regulation of DNA-templated transcription
GO:0006357	regulation of transcription by RNA polymerase II
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0006897	endocytosis
GO:0007165	signal transduction
GO:0007186	G protein-coupled receptor signaling pathway
GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007601	visual perception
GO:0007602	phototransduction
GO:0008277	regulation of G protein-coupled receptor signaling pathway
GO:0008284	positive regulation of cell population proliferation
GO:0009410	response to xenobiotic stimulus
GO:0009968	negative regulation of signal transduction
GO:0015031	protein transport
GO:0016567	protein ubiquitination
GO:0031397	negative regulation of protein ubiquitination
GO:0031398	positive regulation of protein ubiquitination
GO:0032715	negative regulation of interleukin-6 production
GO:0032717	negative regulation of interleukin-8 production
GO:0034393	positive regulation of smooth muscle cell apoptotic process
GO:0035025	positive regulation of Rho protein signal transduction
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0042699	follicle-stimulating hormone signaling pathway
GO:0042981	regulation of apoptotic process
GO:0043066	negative regulation of apoptotic process
GO:0043149	stress fiber assembly
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043278	response to morphine
GO:0043410	positive regulation of MAPK cascade
GO:0043524	negative regulation of neuron apoptotic process
GO:0045746	negative regulation of Notch signaling pathway
GO:0045944	positive regulation of transcription by RNA polymerase II
GO:0050975	sensory perception of touch
GO:0070373	negative regulation of ERK1 and ERK2 cascade
GO:0070374	positive regulation of ERK1 and ERK2 cascade

Biological Process

GO:0001934

positive regulation of protein phosphorylation

GO:0002031

G protein-coupled receptor internalization

GO:0002092

positive regulation of receptor internalization

GO:0006355

regulation of DNA-templated transcription

GO:0006357

regulation of transcription by RNA polymerase II

GO:0006511

ubiquitin-dependent protein catabolic process

GO:0006897

endocytosis

GO:0007165

signal transduction

GO:0007186

G protein-coupled receptor signaling pathway

GO:0007188

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

GO:0007601

visual perception

GO:0007602

phototransduction

GO:0008277

regulation of G protein-coupled receptor signaling pathway

GO:0008284

positive regulation of cell population proliferation

GO:0009410

response to xenobiotic stimulus

GO:0009968

negative regulation of signal transduction

GO:0015031

protein transport

GO:0016567

protein ubiquitination

GO:0031397

negative regulation of protein ubiquitination

GO:0031398

positive regulation of protein ubiquitination

GO:0032715

negative regulation of interleukin-6 production

GO:0032717

negative regulation of interleukin-8 production

GO:0034393

positive regulation of smooth muscle cell apoptotic process

GO:0035025

positive regulation of Rho protein signal transduction

GO:0035774

positive regulation of insulin secretion involved in cellular response to glucose stimulus

GO:0042699

follicle-stimulating hormone signaling pathway

GO:0042981

regulation of apoptotic process

GO:0043066

negative regulation of apoptotic process

GO:0043149

stress fiber assembly

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

GO:0043278

response to morphine

GO:0043410

positive regulation of MAPK cascade

GO:0043524

negative regulation of neuron apoptotic process

GO:0045746

negative regulation of Notch signaling pathway

GO:0045944

positive regulation of transcription by RNA polymerase II

GO:0050975

sensory perception of touch

GO:0070373

negative regulation of ERK1 and ERK2 cascade

GO:0070374

positive regulation of ERK1 and ERK2 cascade

	Cellular Component
GO:0000785	chromatin
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005768	endosome
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0005905	clathrin-coated pit
GO:0014069	postsynaptic density
GO:0016323	basolateral plasma membrane
GO:0031143	pseudopodium
GO:0031410	cytoplasmic vesicle
GO:0042995	cell projection
GO:0043197	dendritic spine
GO:0045211	postsynaptic membrane
GO:0098978	glutamatergic synapse

Cellular Component

chromatin

nucleus

cytoplasm

endosome

cytosol