Structure of PDB 8gk8 Chain B

Receptor sequence
>8gk8B (length=1053) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
QIKKLLVANRGEIAIRIFAAAAELDISTVAIYSNEDKSSLHRYKADESYL
VGSDLGPAESYLNIERIIDVAKQANVDAIHPGYGFLSENEQFARRCAEEG
IKFIGPHLEHLDMFGDKVKARTTAIKADLPVIPGTDGPIKSYELAKEFAE
EAGFPLMIKAMRIVREESELEDAFHRAKSEAEKSNSEVYIERYIDNPKHI
EVQVIGDEHGNIVHLFERDCSVQRRHQKVVEVAPSVGLSPTLRQRICDAA
IQLMENIKYVNAGTVEFLVSGDEFFFIEVNPRVQVEHTITEMVTGIDIVK
TQILVAAGADLFGEEINMPQQKDITTLGYAIQCRITTEDPLNDFMPDTGT
IIAYRSSGGFGVRLDAGDGFQGAEISPYYDSLLVKLSTHAISFKQAEEKM
VRSLREMRIRGVKTNIPFLINVMKNKKFTSGDYTTKFIEETPELFDIQPS
LDRGTKTLEYIGNVTINGFPNVEKRPKPDYELASIPTVSSSKIASFSGTK
QLLDEVGPKGVAEWVKKQDDVLLTDTTFRDAHQSLLATRVRTKDMINIAS
KTADVFKDGFSLEMWGGATFDVAYNFLKENPWERLERLRKAIPNVLFQML
LRASNAVGYKNYPDNVIHKFVQESAKAGIDVFRIFDSLNWVDQMKVANEA
VQEAGKISEGTICYTGDILNPERSNIYTLEYYVKLAKELEREGFHILAIK
DMAGLLKPKAAYELIGELKSAVDLPIHLHTHDTSGNGLLTYKQAIDAGVD
IIDTAVASMSGLTSQPSANSLYYALNGFPRHLRTDIEGMESLSHYWSTVR
TYYSDFESDIKSPNTEIYQHEMPGGQYSNLSQQAKSLGLGERFDEVKDMY
RRVNFLFGDIVKVTPSSKVVGDMALYMVQNDLDEQSVITDGYKLDFPESV
VSFFKGEIGQPVNGFNKDLQAVILKGQEALTARPGEYLEPVDFEKVRELL
EEEQQGPVTEQDIISYVLYPKVYEQYIQTRNQYGNLSLLDTPTFFFGMRN
GETVEIEIDKGKRLIIKLETISEPDENGNRTIYYAMNGQARRIYIKDENM
KME
3D structure
PDB8gk8 R21A Staphylococcus aureus pyruvate carboxylase
ChainB
Resolution2.68 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.4.1.1: pyruvate carboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B D542 K712 H741 H743 D530 K700 H729 H731
BS02 BTI B Y472 V476 G480 F481 P482 F588 K590 Y460 V464 G468 F469 P470 F576 K578
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004736 pyruvate carboxylase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006090 pyruvate metabolic process
GO:0006094 gluconeogenesis
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8gk8, PDBe:8gk8, PDBj:8gk8
PDBsum8gk8
PubMed37603581
UniProtA0A3A5LTU8

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