Structure of PDB 8gju Chain B

Receptor sequence
>8gjuB (length=330) Species: 9606 (Homo sapiens) [Search protein sequence]
DKEQRFVDKLYTGLIQGQRACLAEAITLVESTHSRKKELAQVLLQKVLLY
HREQEQSNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAV
DPSSCTSGGSLLGDKTRMTELSRDMNAYIRPSPTRGTLGGVTRTTNEAIL
LCEGAGYDIILIETVGVGQSEFAVADMVDMFVLLLPPAGGGIKRGIIEMA
DLVAVTKSDGDLIVPARRIQAEYVSALKLLRKRSQVWKPKVIRISARSGE
GISEMWDKMKDFQDLMLASGELTAKRRKQQKVWMWNLIQESVLEHFRTHP
TVREQIPLLEQKVLIGALSPGLAADFLLKA
3D structure
PDB8gju Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B 12 delivery and repair.
ChainB
Resolution2.79 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B G153 A154 G155 K156 S157 T158 R196 K290 D292 R330 G74 A75 G76 K77 S78 T79 R117 K207 D209 R247
BS02 MG B S157 D193 E242 S78 D114 E163
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:8gju, PDBe:8gju, PDBj:8gju
PDBsum8gju
PubMed37468522
UniProtQ8IVH4|MMAA_HUMAN Methylmalonic aciduria type A protein, mitochondrial (Gene Name=MMAA)

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