Structure of PDB 8get Chain B

Receptor sequence
>8getB (length=644) Species: 301301 (Roseburia hominis) [Search protein sequence]
MREVINFNTKWAFTKEATEVPKEMPEKWYWVTLPHSWNEIDGQDGGNDYY
RGTCYYAKQLKKSELPEADCYYLELRGANASADVYVNGKAVAHHDGGYST
WRVDITKELTEEENLIVIAVENGVNDRVYPQNADFTFYGGLYRDVNIIAV
NKSHFDLDYYGGPGIKVTPEIKGADASVEVEVFLTNAAADQKLVYTVKDA
EGKEVAKTETAAGETKAVLSIPAVHLWNGKKDPYLYTAEVALVSGEEAVD
AVSTRFGCRTFEIDPERGFILNGEEYPLRGVSRHQDRWGIGNALLPEHHR
EDIDLICELGATTIRLAHYQHDQYFYDLCDERGLVIWAEIPYISSHMPNG
RENTISQMKELVVQNYNHPSIVVWGLSNEITMAGSSDEDLLENHRILNDM
VHEMDHTRLTTIAVVSMCDIHDPYIQIPDVISYNHYFGWYGGDVSMNGPW
MDNFHKEFPNIPLGMSEYGCEALNWHTSDPKQGDYTEEYQAYYHEEMIKQ
LFTRKYIWATHVWNMFDFGADARNEGGENGQNHKGLVTFDRKYKKDSFYA
YKAWLSDEPFVHLCGKRYVDRVEDTTKVTVYSNLPEVELFVNGKSAGKLQ
AEDHFFHFEVPNVGESTLVAVAGEYKDESHIRKVDTFNEEYSLK
3D structure
PDB8get Diverse Human Therapeutics Impact Hormone and Neurotransmitter Homeostasis by Inhibiting Gut Microbial Enzymes
ChainB
Resolution2.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BDP B D133 H317 E378 Y435 E466 W512 F517 R522 N531 K533 D134 H318 E379 Y436 E467 W513 F518 R523 N532 K534
BS02 FMN B D155 Y158 K165 F182 V362 Y365 M403 D156 Y159 K166 F183 V363 Y366 M404
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004565 beta-galactosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8get, PDBe:8get, PDBj:8get
PDBsum8get
PubMed38754417
UniProtA0A395V8I7

[Back to BioLiP]