Structure of PDB 8gbl Chain B

Receptor sequence
>8gblB (length=253) Species: 9606 (Homo sapiens) [Search protein sequence]
SSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLAT
PLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVV
ITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGK
GAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDR
ELAHCDLCLVVGTSSAAMFAPQVAARGVPVAEFNTERFHFQGPCGTTLPE
ALA
3D structure
PDB8gbl Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice
ChainB
Resolution2.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C166 C169 C207 C212 C129 C132 C170 C175
External links
PDB RCSB:8gbl, PDBe:8gbl, PDBj:8gbl
PDBsum8gbl
PubMed38846003
UniProtQ9NXA8|SIR5_HUMAN NAD-dependent protein deacylase sirtuin-5, mitochondrial (Gene Name=SIRT5)

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